Yea, I feel you. This game is actually a challenge, b/c you HAVE to play more like a college basketball team. In NBA games, there is more isolation, 1 on 1 involved. So you should learn who's good @ what and play to your team strengths.
On defense, play 2-3 zone. both gaurds @ the top of the key, SF and both big men down low. Play w/ either the center or PF and just hog the lane. Mak sure you rotate w/ the ball.
On offense, Use the motion offense, and learn the timing of when you take a shot. Its all really timing.